WebMonday, July 5, 2024 Douglass F. Taber University of Delaware The Wong/Peng Synthesis of Cryptotrione Cryptotrione ( 3 ), isolated from the Japanese cedar Cryptomeria japonica, showed activity against human oral epidermoid carcinoma KB cells. WebThree pivotal reactions, namely, enyne cycloisomerization, polyene cyclization, and quinone methide formation, are applied to synthesize the complex polycyclic skeleton of …
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WebJun 20, 2012 · An efficient stereoselective approach to the tetracyclic core of Cryptotrione, involving an asymmetric Michael addition, ring-closing metathesis, and subsequent … WebJun 20, 2012 · An efficient stereoselective approach to the tetracyclic core of Cryptotrione, involving an asymmetric Michael addition, ring-closing metathesis, and subsequent cyclopropanation, is described. Full text links Read article at publisher's site (DOI): 10.1039/c2ob25923k References Articles referenced by this article (32) camping les houblonnieres boeschepe
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WebApache Server at chemeurope.com Port 80 WebTotal Synthesis of Cryptotrione Angew. Chem. Int. Ed. 2024, DOI: 10.1002/anie.202409255. Synthesis of (±)-Cryptotrione Significance: Cryptotrione was isolated from the bark of Cryptomeria japonica in 2010. It has antican-cer activity against human oral epidermoid carcino-ma KB cells. Additionally, it consists of an unprece- WebThe first total syntheses of (±)-rhabdastrellic acid A and (±)-stelletin E, highly cytotoxic isomalabaricane triterpenoids, have been accomplished in a linear sequence of 14 steps from commercial geranylacetone. The exceptionally strained trans-syn-trans-perhydrobenz[e]indene core characteristic of the isomalabaricanes is efficiently accessed … firth house facebook