Fsp1 promoter

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August undefined, 2024

WebThe promoter/enhancer region driving this gene is active in fibroblasts but not in epithelium, mesangial cells or embryonic endoderm. During development, FSP1 is first detected by in situ hybridization after day 8.5 as a postgastrulation event, and is associated with cells of mesenchymal origin or of fibroblastic phenotype. WebThe Burn is a news and lifestyle website primarily focused on restaurants, retail, shopping centers, entertainment venues and other topics that have people buzzing in Loudoun County, Virginia.

A targetable CoQ-FSP1 axis drives ferroptosis- and …

WebNo two clients are identical at HSP Direct. Your program will be matched with a team of experienced professionals who have a passion for your cause and are excited to build a unique fundraising program that matches your needs. WebJul 31, 2024 · In T- and B- acute lymphoblastic leukemia (ALL) cell lines and patient biopsies, the promoter of the gene coding for FSP1 is hypermethylated, silencing the expression of FSP1and creating a selective dependency on GSH-centered anti … sporcle injustice league members

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WebSep 1, 2024 · FSP1 gene structure is shown on the top part of the heatmap highlighting the CpG island found in the promoter region. D. FSP1 promoter methylation determined by bisulfite sequencing in CTV-1, Jurkat and K562 cells (sequenced chromosomal region: chr10:71892987 to chr10:71892584, hg19). E. WebApr 30, 2013 · FSP1 can be expressed by different cell types of mesenchymal origin. We found FSP1 was mainly expressed by procollagen I + fibroblasts in skin tissue treated with methylcholanthrene/oil. Also, … WebJul 9, 2024 · Using mice that express GFP under the FSP1 or αSMA promoter, we characterized two non-overlapping fibroblast subtypes from mouse hearts after myocardial infarction. sporcle india cricket top 10

Lack of specificity of fibroblast-specific protein 1 in cardiac ...

AIFM2 Gene - GeneCards FSP1 Protein FSP1 Antibody

WebMar 21, 2024 · UniProtKB/Swiss-Prot Summary for AIFM2 Gene. A NAD (P)H-dependent oxidoreductase that acts as a key inhibitor of ferroptosis (PubMed: 31634899, 31634900, 35922516 ). At the plasma membrane, catalyzes reduction of coenzyme Q/ubiquinone-10 to ubiquinol-10, a lipophilic radical-trapping antioxidant that prevents lipid oxidative damage … WebMar 3, 2024 · The Fsp1-Flpo allele consists in the Flpo recombinase under the control of the Fsp1 (fibroblast-specific promoter 1) promoter. The FSF TGFβ CA allele consists in a transgene encoding a constitutively active mutant form of TGFβ (TGFβ CA ) under the control of a Frt-STOP-Frt (FSF) cassette. shell shack menu dallasWebApr 9, 2024 · For the fluorescence labeling of tumor cells undergoing EMT, Fischer et al. 67 developed a transgenic mouse model using a fibroblast-specific marker-dependent fluorescence switching system, in which the FSP1 promoter drives the Cre-lox recombinase system to induce the RFP-to-GFP conversion in tumor cells undergoing EMT (Figure 4). sporcle inc

"WebThe promoter/enhancer region driving this gene is active in fibroblasts but not in epithelium, mesangial cells or embryonic endoderm. During development, FSP1 is first detected by in situ hybridization after day 8.5 as a postgastrulation event, and is associated with cells of mesenchymal origin or of fibroblastic phenotype. " - Fsp1 promoter

Fsp1 promoter

Fibroblast-Specific Protein 1/S100A4–Positive Cells Prevent Carcinoma

WebNov 25, 2024 · Fibroblast-specific protein 1 (FSP1, also referred to as S100A4) is considered as a marker of fibroblasts in different organs undergoing tissue remodeling and could serve as a sensitive and ... WebMar 21, 2024 · fsp1_human,q9brq8 EnzymeRegulation: The modification by 4-hydroxy-2-nonenal (HNE) adduction in mitochondria results in loss of the oxidoreductase activity and activation of a novel function in mitochondrial oxidative stress signaling.

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WebVisit a Premier eye doctor to get more out of your VSP vision insurance! VSP members get more and save more through extra offers that are exclusive to Premier Program locations. WebApr 15, 2016 · Specifically, the MMTV-PyMT, Rosa26-RFP-GFP, and Fsp1-Cre triple transgenic mouse model was used to monitor the conversion of RFP-positive epithelial cells to GFP-positive mesenchymal cells in mammary tumors under the control of the Fsp1 (ATL1) promoter, a gate-keeper of EMT initiation.

WebNov 23, 2010 · Therefore, we tested whether FSP1 is a marker of myofibroblasts characterized by expression of mesenchymal markers including desmin and αSMA. For this purpose, FSP1-GFP reporter mice in which the FSP1 promoter drives GFP expression … WebJan 4, 2024 · An F1 sponsors gets a return on their investment in the following ways; Helps to build brand awareness. Drives excitement around the brand. Increased product or service sales. Market expansion. Helps to market new products or services. Drive more website …

WebNov 1, 2013 · Fibroblast-specific protein (FSP)1 has been suggested as a fibroblast-specific marker in normal and fibrotic tissues; FSP1 reporter mice and FSP1-Cre-driven gene deletion are considered reliable strategies to investigate fibroblast biology. Because … WebOFFICE OF PARTNERSHIPS AND PUBLIC ENGAGEMENT Farming Opportunities Training and Outreach Grant Program What is the FOTO Grants Program? The Farming Opportunities Training and Outreach (FOTO)

WebMar 5, 2024 · FSP1 promoter assay was done as described in ref. 28. FSP1 promoter construct plasmid containing 1.0–1.3 kb insert, corresponding to the 5′-flanking sequence located ~1.3 kb upstream and …

WebApr 22, 2024 · In this study, we identify ferroptosis suppressor protein 1 (FSP1, also known as AIFM2) as a transcriptional target of nuclear factor erythroid 2-related factor 2 (NRF2) and reveal that the ubiquinone (CoQ)-FSP1 axis mediates ferroptosis- and radiation- … sporcle huddersfield townWebTel: 703.793.3220. Fax: 703.723.5405. E-mail: [email protected]. Directions from the Washington, D.C., I-495 Capital Beltway: From the I-495 Capital Beltway, follow signs for Dulles Airport Access and Toll Road (Rte. 267). Proceed westbound and remain on the … sporcle ian mcshaneWebApr 22, 2024 · Likewise, KEAP1 deletion increased FSP1 promoter-luciferase activities and this increase was abolished by ARE mutations (Fig. 3i). Fig. 3: KEAP1 regulates FSP1 through NRF2-mediated transcription. sporcle international football xiWebOct 19, 2024 · Next, two antioxidant response elements (AREs) which are well-established NRF2 binding motif were found in FSP1 gene promoter regions. ChIP-qPCR assay was performed to verify the increased binding of NRF2 to the AREs of FSP1 upon KEAP1 knockout. Besides, NRF2 activator treatment or KEAP1 deficiency dramatically … sporcle iowa countiesWebMay 13, 2013 · FSP1 cells in the infarcted and pressure-overloaded myocar-dium, we used transgenic mice with GFP expression driven by the FSP1 promoter. Using ﬂow cytometry and immunohisto-chemical staining, we found marked inﬁltration of the infarcted and remodeling myocardium with FSP1 cells. In the infarct, almost half of the FSP1 cells … shell shack order onlineWebFeb 4, 2016 · Surprisingly, the majority of cells in the primary tumor and lung metastasis are RFP +, suggesting the absence of Fsp1 promoter activation, and by extension, EMT. Similar results were observed in the MMTV-Neu model or when the Vimentin promoter was used. The researchers further showed that inhibition of EMT by overexpressing miR-200 … sporcle images not loadingWeb1 Prostate-Specific Promoters. The rat probasin (PB) promoter and its derivatives, which include the minimal PB promoter,17 the long 12 kb PB promoter, 18 and the composite ARR2PB promoter, 19 are the most commonly used promoters for targeting expression of genes of interest to the prostate epithelium. PB is an abundant protein that belongs to ... sporcle ireland counties